You still can't play with friends in different regions, but you can communicate with players across Europe, the Americas, and Asia which is a nice addition to the app. Of course, players are hoping this leads to even more in the future, like cross-region characters, but Blizzard has not indicated that is planned.
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Global Cross-Region Friends Lists Coming to Battle.net
Blizzard has announced that Global Friends Lists are coming to Battle.net in a June 8th update. Thanks to stanzillaz for spotting this.
