As the blue post points out, while this is a heavy limitation for characters that do multiple types of content, there are very robust addon solutions that help alleviate these issues.
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Blizzard on Limit of Talent Loadouts – Storage Limitations, Addon Solutions
Blizzard replied to questions about the limit of the character talent loadout settings. Currently, players can only store up to 10 different loadouts, which, according to Blizzard, was added due to storage concerns since loadouts are stored together with other character data.
