Of particular note, user Zolmation on the Blizzard Forums has created a comprehensive list for all zones on which quests are drop-only. We've summarized their findings below!
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We've recently covered the Dungeon Side Quests available in Diablo 4, but for many completionists, you may be hitting the point where each zone is missing a handful of quests with no questgiver in sight. Don't worry - several players have already found these straggler drop quests!